ICD-10 Code E72.8 – Other specified disorders of amino-acid metabolism (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E72.8 – Other specified disorders of amino-acid metabolism
What it is
E72.8 identifies a disorder of amino-acid metabolism that does not fit a more specific ICD-10-CM code. Use it when documentation confirms an amino-acid metabolic condition, but the exact type is named as other specified.
Clinical signs
Clinical features vary; refer to documentation. Findings may reflect an inherited metabolic disorder with abnormal handling of one or more amino acids, but the record must support the specific diagnosis rather than a general metabolic concern.
When to use this code
Use this code when the provider documents a specified amino-acid metabolism disorder and no more precise code is available. It also fits cases where the condition is clearly identified in the chart as “other specified” or by a named variant not indexed elsewhere.
Check documentation if the note only mentions abnormal amino-acid testing, suspected inborn error, or nonspecific metabolic disease. You should code the confirmed diagnosis, not a screening result or an undetermined metabolic abnormality.
Do not use for
Do not use E72.8 for unspecified metabolic disorders or for amino-acid conditions with a more specific ICD-10-CM code. If the provider documents only a rule-out or abnormal lab finding, choose a different code or await clarification.
Coding tip
Look for the exact provider wording; “other specified” supports E72.8 only when the record names a definite amino-acid disorder.