ICD-10 Code E72.538 – Other specified primary hyperoxaluria (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E72.538 – Other specified primary hyperoxaluria
What it is
E72.538 identifies a form of primary hyperoxaluria that is specified in the record but does not fit the other named primary hyperoxaluria codes. It reflects an inherited disorder of oxalate overproduction.
Clinical signs
Clinical features vary; refer to documentation. Commonly documented findings include recurrent kidney stones, nephrocalcinosis, hematuria, and progressive kidney impairment. Diagnosis is usually supported by specialist evaluation and genetic or metabolic testing.
When to use this code
Use this code when the provider documents primary hyperoxaluria and names a specific type that is not otherwise classified in the code set. It is also appropriate when the chart clearly states “other specified primary hyperoxaluria.” Check documentation if the record only says hyperoxaluria without the primary designation.
Do not use for
Do not use this code for secondary hyperoxaluria, nonspecific hyperoxaluria, or kidney stones without documented primary hyperoxaluria. If the type is not clearly specified, code only what the documentation supports.
Coding tip
Confirm that “primary” and “other specified” are both documented before assigning E72.538.