ICD-10 Code E72.53 – Primary hyperoxaluria (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E72.53 – Primary hyperoxaluria
What it is
Primary hyperoxaluria is an inherited disorder that causes the body to make too much oxalate. The excess oxalate can build up in the kidneys and other tissues.
Clinical signs
Clinical features vary; refer to documentation. Common findings include recurrent kidney stones, blood in the urine, kidney impairment, or nephrocalcinosis. Diagnosis is usually supported by genetic or biochemical evidence.
When to use this code
Use E72.53 when the provider documents primary hyperoxaluria, including a confirmed hereditary oxalate overproduction disorder. Code it for encounters focused on evaluation, monitoring, or complications linked to this diagnosis. Do not use it for nonspecific hyperoxaluria without documentation of a primary form.
Do not use for
Do not use this code for secondary hyperoxaluria, kidney stones alone, or oxalate abnormalities without a documented primary disorder. Check documentation if the cause is unclear.
Coding tip
Assign E72.53 only when the record clearly states primary hyperoxaluria or an equivalent inherited diagnosis.