ICD-10 Code E34.51 – Complete androgen insensitivity syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E34.51 – Complete androgen insensitivity syndrome
What it is
E34.51 identifies complete androgen insensitivity syndrome, a condition in which a person with a 46,XY karyotype does not respond to androgens. This leads to typical female external genital development despite testes being present.
Clinical signs
Common findings include typical female external genitalia, absent or scant pubic and axillary hair, and primary amenorrhea. Clinical features vary; refer to documentation, especially when diagnosis is confirmed by genetics or endocrine evaluation.
When to use this code
Use E34.51 when the record specifically documents complete androgen insensitivity syndrome or complete testicular feminization. Apply it for confirmed cases during evaluation of primary amenorrhea, atypical sex development, or related genetic counseling notes. Check documentation if the chart only says “androgen insensitivity” without specifying complete form.
Do not use for
Do not use this code for partial or mild androgen insensitivity syndrome, which may require a different diagnosis code. Do not use it when the diagnosis is uncertain or when documentation is limited to ambiguous disorder of sex development terminology.
Coding tip
Assign E34.51 only when the provider clearly documents the complete form; otherwise, query for specificity.