ICD-10 Code E31.8 – Other polyglandular dysfunction (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E31.8 – Other polyglandular dysfunction
What it is
E31.8 identifies other polyglandular dysfunction, meaning a disorder involving more than one endocrine gland that does not fit a more specific ICD-10 category. Use it when documentation names polyglandular dysfunction without a precise subtype.
Clinical signs
Clinical features vary; refer to documentation. Patients may have signs of multiple endocrine gland abnormalities, such as hormone imbalance, autoimmune endocrine disease, or related endocrine insufficiency.
When to use this code
Use this code when the provider documents other polyglandular dysfunction and does not specify a more exact diagnosis. It may apply when several endocrine glands are involved but the record does not support a distinct polyglandular syndrome. Check documentation for the exact glands affected and any linked endocrine disorders.
Do not use for
Do not use this code for a clearly documented, more specific polyglandular syndrome or for a single-gland endocrine disorder. If the chart names a different endocrine condition, code that condition instead.
Coding tip
Code E31.8 only when the provider’s wording supports polyglandular dysfunction and no more specific code is available.