ICD-10 Code E21.5 – Disorder of parathyroid gland, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Disorder of parathyroid gland, unspecified is E21.5.
2026 ICD-10-CM Diagnosis Code E21.5 – Disorder of parathyroid gland, unspecified

What it is

E21.5 identifies a parathyroid gland disorder when the record does not specify the exact type. Use it for nonspecific parathyroid dysfunction documented by the clinician.

Clinical signs

Clinical features vary; refer to documentation. Patients may have signs consistent with parathyroid dysfunction, but the chart should support an unspecified gland disorder rather than a named endocrine condition.

When to use this code

Use E21.5 when the provider documents a parathyroid gland disorder without further detail. It is appropriate when the note confirms a parathyroid problem but does not identify primary, secondary, or other specific forms. Check documentation if the record suggests a more precise diagnosis.

Do not use for

Do not use this code if the documentation names a specific parathyroid disorder, such as primary or secondary hyperparathyroidism. Avoid it when the condition is better described by another endocrine diagnosis.

Coding tip

Code the most specific parathyroid diagnosis supported by the record; use E21.5 only when the provider leaves the disorder unspecified.

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