ICD-10 Code E10.43 – Type 1 diabetes mellitus with diabetic autonomic (poly)neuropathy (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Type 1 diabetes mellitus with diabetic autonomic (poly)neuropathy is E10.43.
2026 ICD-10-CM Diagnosis Code E10.43 – Type 1 diabetes mellitus with diabetic autonomic (poly)neuropathy

What it is

This code identifies type 1 diabetes complicated by diabetic autonomic neuropathy, meaning damage to the nerves that control involuntary body functions. It applies when the record links the autonomic neuropathy to type 1 diabetes.

Clinical signs

Clinical features vary; refer to documentation. Common findings may include autonomic symptoms such as abnormal sweating, resting tachycardia, gastrointestinal dysmotility, or orthostatic intolerance, when documented as diabetic in origin.

When to use this code

Use E10.43 when the provider documents type 1 diabetes with autonomic neuropathy, autonomic polyneuropathy, or diabetic autonomic nerve involvement. The diabetes and neuropathy must be linked in the record. If the type or neuropathy relationship is unclear, check documentation before coding.

Do not use for

Do not use this code for peripheral neuropathy without autonomic involvement, or when neuropathy is not documented as diabetic. Check documentation if the record supports a different diabetes type or another neurologic cause.

Coding tip

Verify that the provider explicitly connects the autonomic neuropathy to type 1 diabetes before assigning E10.43.

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