ICD-10 Code E09.331 – Drug or chemical induced diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Drug or chemical induced diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema is E09.331.
2026 ICD-10-CM Diagnosis Code E09.331 – Drug or chemical induced diabetes mellitus with moderate nonproliferative diabetic retinopathy with macular edema

What it is

This code identifies diabetes caused by a drug or chemical, with moderate nonproliferative diabetic retinopathy and macular edema in one or both eyes. Use it when documentation links the diabetes to an external substance and confirms the eye complication.

Clinical signs

Clinical features vary; refer to documentation. Standard findings include diabetic retinal changes described as moderate nonproliferative retinopathy, plus macular edema noted on the exam or imaging.

When to use this code

Use E09.331 when the provider documents drug- or chemical-induced diabetes and specifically states moderate nonproliferative diabetic retinopathy with macular edema. This code applies whether the eye involvement is unilateral or bilateral, unless laterality is documented more specifically elsewhere in the record. Check documentation if the causal substance or eye findings are unclear.

Do not use for

Do not use this code for diabetes without a documented drug or chemical cause, or for retinopathy without macular edema. If the record shows a different severity or a different diabetic eye complication, choose the matching code.

Coding tip

Verify both the diabetes cause and the exact retinal wording before assigning E09.331.

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