ICD-10 Code D75.821 – Non-immune heparin-induced thrombocytopenia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D75.821 – Non-immune heparin-induced thrombocytopenia
What it is
This code identifies a drop in platelet count linked to heparin exposure that is not caused by an immune-mediated reaction. Use it when the record specifically documents non-immune heparin-induced thrombocytopenia.
Clinical signs
Clinical features vary; refer to documentation. The chart may describe thrombocytopenia occurring after heparin use without evidence of heparin-induced thrombocytopenia immune antibodies or classic HIT complications.
When to use this code
Use D75.821 when the provider documents non-immune heparin-induced thrombocytopenia, including heparin-associated platelet decline that is not immune mediated. Apply it when the diagnosis is clearly stated in the assessment, discharge summary, or problem list. Check documentation if the record only says “HIT” without specifying the type.
Do not use for
Do not use this code for immune-mediated HIT or when the provider documents only suspected thrombocytopenia without a confirmed heparin relationship. If the type is unclear, check documentation.
Coding tip
Code the exact type of heparin-induced thrombocytopenia documented; “HIT” alone is not enough.