ICD-10 Code D61.2 – Aplastic anemia due to other external agents (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Aplastic anemia due to other external agents is D61.2.
2026 ICD-10-CM Diagnosis Code D61.2 – Aplastic anemia due to other external agents

What it is

D61.2 identifies aplastic anemia caused by an external agent, such as a drug, toxin, or other outside exposure. It means the bone marrow is failing to produce enough blood cells because of that exposure.

Clinical signs

Patients may show signs of pancytopenia, including fatigue, pallor, infections, or easy bruising. Clinical features vary; refer to documentation for the specific cause and marrow findings.

When to use this code

Use this code when the record links aplastic anemia to an external agent and the provider documents that causal relationship. It applies when the anemia is not described as hereditary, idiopathic, or due to another classified condition. Check documentation if the exposure is suspected but not confirmed.

Do not use for

Do not use D61.2 for aplastic anemia without a documented external cause. Do not use it when the anemia is better classified as congenital, drug-induced under a more specific code, or due to another documented disorder.

Coding tip

Look for the exact external agent in the note and code it only when the provider clearly states causation.

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