ICD-10 Code D58.2 – Other hemoglobinopathies (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other hemoglobinopathies is D58.2.
2026 ICD-10-CM Diagnosis Code D58.2 – Other hemoglobinopathies

What it is

D58.2 identifies inherited or acquired disorders involving abnormal hemoglobin that do not fit a more specific hemoglobinopathy code. Use it when documentation states “other hemoglobinopathy” or a similar nonspecific hemoglobin disorder.

Clinical signs

Clinical features vary; refer to documentation. Patients may have anemia, jaundice, fatigue, or evidence of hemolysis, but the exact presentation depends on the underlying hemoglobin abnormality.

When to use this code

Use D58.2 when the provider documents a hemoglobinopathy that is not named elsewhere in ICD-10-CM. It also fits cases where the record confirms a hemoglobin disorder but does not specify a more precise subtype. Check documentation if the condition is a thalassemia, sickle cell disorder, or another coded entity.

Do not use for

Do not use this code for sickle cell disorders, thalassemias, or other more specific hemoglobin-related diagnoses. If the record names a defined condition, code that diagnosis instead.

Coding tip

Query the provider when the chart says “hemoglobinopathy” without details, because a more specific code may be available.

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