ICD-10 Code D46.2 – Refractory anemia with excess of blasts [RAEB] (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D46.2 – Refractory anemia with excess of blasts [RAEB]
What it is
D46.2 identifies refractory anemia with excess of blasts, a myelodysplastic syndrome with abnormal blood cell production and increased immature precursor cells in the bone marrow. Use this code for the documented RAEB diagnosis, not for nonspecific anemia.
Clinical signs
Clinical features vary; refer to documentation. Common findings include persistent cytopenias, marrow dysplasia, and evidence of excess blasts on hematology evaluation or bone marrow examination.
When to use this code
Use D46.2 when the provider documents RAEB, including older terminology or a myelodysplastic syndrome subtype with excess blasts. It is appropriate when the record supports the specific diagnosis rather than a general marrow disorder. If the note is unclear, check documentation.
Do not use for
Do not use this code for simple anemia, unspecified myelodysplastic syndrome, or other MDS subtypes without excess blasts. If the condition is described differently, code the documented diagnosis.
Coding tip
Code the most specific documented MDS subtype and confirm whether RAEB is explicitly stated in the assessment or pathology report.