ICD-10 Code D40.0 – Neoplasm of uncertain behavior of prostate (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Neoplasm of uncertain behavior of prostate is D40.0.
2026 ICD-10-CM Diagnosis Code D40.0 – Neoplasm of uncertain behavior of prostate

What it is

D40.0 identifies a prostate growth whose behavior is uncertain, meaning the record does not clearly show whether it is benign or malignant. Use it for documented neoplasms of the prostate when the pathology or provider assessment remains indeterminate.

Clinical signs

Clinical features vary; refer to documentation. Patients may have a prostate mass, abnormal imaging, or biopsy findings that do not establish a definite malignant or benign diagnosis.

When to use this code

Use D40.0 when the provider documents a neoplasm of the prostate and specifically states uncertain behavior. It is appropriate when pathology, imaging, or clinical assessment has not resolved the lesion’s nature. Code only what is documented and avoid assuming cancer or benign disease.

Do not use for

Do not use this code for clearly benign prostate conditions or confirmed malignant prostate cancer. If the documentation does not specify uncertain behavior, check documentation for the correct diagnosis.

Coding tip

Look for the exact phrase “uncertain behavior” in the assessment or pathology report before assigning D40.0.

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