ICD-10 Code C92.52 – Acute myelomonocytic leukemia, in relapse (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C92.52 – Acute myelomonocytic leukemia, in relapse
What it is
C92.52 identifies acute myelomonocytic leukemia that has returned after a period of remission. Use it when documentation states the leukemia is relapsed, recurrent, or no longer in complete remission.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings in relapse include worsening cytopenias, circulating blasts, marrow involvement, and return of leukemia-related symptoms such as fatigue, infection, or bleeding.
When to use this code
Use this code when the provider documents acute myelomonocytic leukemia as “in relapse,” “recurrent,” or similar language. It also fits follow-up encounters where the active disease has reappeared after prior remission. Check the record for the exact leukemia subtype and disease status.
Do not use for
Do not use this code for newly diagnosed acute myelomonocytic leukemia, remission status, or history of leukemia without current relapse. If the subtype or relapse status is unclear, check documentation.
Coding tip
Verify both the specific leukemia subtype and the relapse wording before assigning C92.52.