ICD-10 Code C92.5 – Acute myelomonocytic leukemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C92.5 – Acute myelomonocytic leukemia
What it is
Acute myelomonocytic leukemia is a subtype of acute myeloid leukemia that involves both myeloid and monocytic cell lines. Use this code when the record specifically identifies this diagnosis.
Clinical signs
Clinical features vary; refer to documentation. Commonly, acute leukemia presents with bone marrow failure findings such as anemia, infection, or bleeding, along with blasts in blood or marrow.
When to use this code
Use C92.5 when the provider documents acute myelomonocytic leukemia, including confirmed AML-M4 terminology. Apply it for initial diagnosis, active treatment, or ongoing care when this specific leukemia type remains documented.
If the note only says acute myeloid leukemia, do not assume this subtype. Check documentation for the exact leukemia classification before assigning the code.
Do not use for
Do not use this code for chronic myeloid disorders, monocytic leukemia without the acute myelomonocytic subtype, or unspecified acute leukemia. Check documentation if the diagnosis is incomplete or conflicting.
Coding tip
Code the most specific leukemia type documented; subtype wording matters, so verify pathology, oncology notes, or discharge diagnoses before assigning C92.5.