ICD-10 Code C82.50 – Diffuse follicle center lymphoma, unspecified site (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C82.50 – Diffuse follicle center lymphoma, unspecified site
What it is
C82.50 identifies diffuse follicle center lymphoma when the site is not specified in the record. It is a non-Hodgkin lymphoma arising from germinal center B cells, documented without a more precise anatomic location.
Clinical signs
Clinical features vary; refer to documentation. Commonly recorded findings include painless lymph node enlargement, systemic “B” symptoms, or extranodal involvement, but the diagnosis should be supported by pathology and the provider’s final statement.
When to use this code
Use C82.50 when the chart clearly states diffuse follicle center lymphoma and no site is identified. It also fits when the provider documents lymphoma of this type but does not specify nodal or extranodal location. Check documentation if another lymphoma subtype is mentioned.
Do not use for
Do not use this code for follicular lymphoma with a documented site, because a more specific code may apply. Do not assign it for suspected lymphoma, other non-Hodgkin lymphoma types, or records that only mention generic “lymphoma.”
Coding tip
Code from the final pathology or provider diagnosis, and confirm that “unspecified site” is truly documented before selecting C82.50.