ICD-10 Code C82.28 – Follicular lymphoma grade III, unspecified, lymph nodes of multiple sites (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C82.28 – Follicular lymphoma grade III, unspecified, lymph nodes of multiple sites
What it is
C82.28 identifies follicular lymphoma grade III when the site is lymph nodes of multiple sites and the grade is not further specified. Use it for a documented follicular B-cell lymphoma involving more than one nodal region.
Clinical signs
Patients may present with painless enlarged lymph nodes in more than one area, such as cervical, axillary, or inguinal nodes. Clinical features vary; refer to documentation for biopsy or pathology confirmation of grade III follicular lymphoma.
When to use this code
Use this code when the record clearly states follicular lymphoma grade III and specifies lymph nodes of multiple sites, but does not provide a more detailed grade subtype. It also fits follow-up or active-care encounters when the diagnosis remains documented. Check documentation if the site or grade is unclear.
Do not use for
Do not use C82.28 for follicular lymphoma involving only one lymph node region, or when the lymphoma is another grade or histology. Do not guess this code from suspected lymphoma without confirmed documentation.
Coding tip
Match both the grade and the multi-site nodal location exactly as documented before assigning C82.28.