ICD-10 Code C81.78 – Other Hodgkin lymphoma, lymph nodes of multiple sites (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C81.78 – Other Hodgkin lymphoma, lymph nodes of multiple sites
What it is
This code identifies Hodgkin lymphoma classified as “other” and involving lymph nodes in multiple sites. Use it when the record specifies this pattern rather than a single nodal region.
Clinical signs
Clinical features vary; refer to documentation. Common findings in Hodgkin lymphoma include enlarged lymph nodes, often painless, and possible systemic symptoms such as fever, night sweats, or weight loss.
When to use this code
Use C81.78 when the provider documents other Hodgkin lymphoma affecting lymph nodes at more than one site and does not assign a more specific subtype. It is appropriate when the record clearly states multiple nodal regions are involved. Check documentation if the site description is incomplete or conflicting.
Do not use for
Do not use this code for Hodgkin lymphoma limited to one lymph node region or for a more specific Hodgkin subtype with its own code. Do not use it when the diagnosis is uncertain or not documented as Hodgkin lymphoma.
Coding tip
Confirm both the Hodgkin lymphoma type and the presence of multiple nodal sites before assigning C81.78.