ICD-10 Code C81.35 – Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limb (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limb is C81.35.
2026 ICD-10-CM Diagnosis Code C81.35 – Lymphocyte depleted Hodgkin lymphoma, lymph nodes of inguinal region and lower limb

What it is

This code identifies lymphocyte-depleted Hodgkin lymphoma involving the inguinal region or lower limb lymph nodes. Use it when documentation specifies this Hodgkin lymphoma subtype and nodal location.

Clinical signs

Clinical features vary; refer to documentation. Hodgkin lymphoma is commonly confirmed by pathology, with enlarged lymph nodes and other lymphoma findings supporting the diagnosis.

When to use this code

Use C81.35 when the provider documents lymphocyte-depleted Hodgkin lymphoma in lymph nodes of the groin, inguinal area, or lower extremity. Code it from a confirmed diagnosis, not from suspicion alone. If the site or subtype is unclear, check documentation.

Do not use for

Do not use this code for other Hodgkin lymphoma subtypes or for lymphoma in unspecified nodes. It also should not be used for suspected disease without confirmed documentation.

Coding tip

Confirm both the histologic subtype and the exact nodal site before assigning C81.35.

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