ICD-10 Code C81.32 – Lymphocyte depleted Hodgkin lymphoma, intrathoracic lymph nodes (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C81.32 – Lymphocyte depleted Hodgkin lymphoma, intrathoracic lymph nodes
What it is
C81.32 identifies Hodgkin lymphoma of the lymphocyte-depleted subtype involving intrathoracic lymph nodes. Use it when documentation specifies both the histology and the thoracic nodal site.
Clinical signs
Clinical features vary; refer to documentation. Common findings in Hodgkin lymphoma include enlarged lymph nodes, systemic “B” symptoms, and mediastinal or other intrathoracic lymph node involvement on imaging or biopsy.
When to use this code
Use this code when the record clearly states lymphocyte-depleted Hodgkin lymphoma and identifies intrathoracic lymph nodes as the involved site. It may be supported by pathology, oncology notes, or imaging that localizes disease to thoracic nodes.
If the site is described more generally, or if another nodal region is documented as the primary site, check documentation before assigning C81.32. Code only when the specificity matches both subtype and anatomic location.
Do not use for
Do not use this code for other Hodgkin lymphoma subtypes or for unspecified Hodgkin lymphoma. Do not use it when intrathoracic involvement is not documented or when the record points to a different lymph node region.
Coding tip
Confirm both the subtype and the exact nodal site in the pathology or oncology note before coding.