ICD-10 Code C22.4 – Other sarcomas of liver (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C22.4 – Other sarcomas of liver
What it is
C22.4 identifies malignant sarcomas arising in the liver that are not classified elsewhere. Use it for primary liver sarcoma diagnoses when documentation does not specify a different liver cancer type.
Clinical signs
Clinical features vary; refer to documentation. Patients may present with a hepatic mass, abdominal pain, enlargement of the liver, or nonspecific constitutional symptoms, and diagnosis is usually confirmed by imaging and pathology.
When to use this code
Use this code when the record clearly states a primary sarcoma of the liver and no more specific histologic or anatomic code applies. It also fits cases documented as other or unspecified hepatic sarcoma. If the tumor is metastatic to the liver, check documentation and code the primary site instead.
Do not use for
Do not use C22.4 for hepatocellular carcinoma, cholangiocarcinoma, or benign liver tumors. Do not assign it for secondary malignant neoplasms of the liver.
Coding tip
Query the provider when the pathology report names a specific sarcoma subtype, because a more precise code may be available.