ICD-10 Code A52.8 – Late syphilis, latent (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A52.8 – Late syphilis, latent
What it is
Late syphilis, latent means a syphilis infection that is present but has no current signs or symptoms. You use this code when documentation shows late latent disease, not active clinical findings.
Clinical signs
Clinical features vary; refer to documentation. Latent syphilis is typically identified by positive serology without symptoms, and late latent disease is generally infection of more than one year’s duration or of unknown duration.
When to use this code
Use A52.8 when the provider documents late latent syphilis, latent syphilis of unknown duration, or asymptomatic late infection. It may also apply when follow-up notes confirm latent disease without evidence of neurosyphilis or other active manifestations.
Do not use for
Do not use this code for primary, secondary, or early latent syphilis, or for neurosyphilis and other symptomatic late syphilis forms. Check documentation if the record describes active lesions or organ involvement.
Coding tip
Code exactly what the provider documents, and confirm whether the infection is late latent, early latent, or unspecified duration.