ICD-10 Code A52.2 – Asymptomatic neurosyphilis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A52.2 – Asymptomatic neurosyphilis
What it is
A52.2 identifies neurosyphilis affecting the nervous system without obvious symptoms. Use it when documentation states asymptomatic neurosyphilis or similar wording.
Clinical signs
Clinical features vary; refer to documentation. This code may be supported by cerebrospinal fluid or neurologic findings indicating syphilis involvement, even when the patient has no clear neurologic complaints.
When to use this code
Use A52.2 when the provider documents asymptomatic neurosyphilis, latent nervous system involvement, or neurosyphilis without symptoms. It may also apply when testing confirms CNS involvement and the record clearly distinguishes it from symptomatic disease. Check documentation if the chart is unclear.
Do not use for
Do not use this code for symptomatic neurosyphilis, ocular syphilis, or otosyphilis unless the record specifically supports asymptomatic CNS involvement. If the provider documents another stage of syphilis, code that condition instead.
Coding tip
Confirm the provider’s wording; “asymptomatic” must be explicit or clearly supported in the record.