ICD-10 Code B16.1 – Acute hepatitis B with delta-agent without hepatic coma (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B16.1 – Acute hepatitis B with delta-agent without hepatic coma
What it is
B16.1 identifies an acute hepatitis B infection occurring with hepatitis D (delta agent), without hepatic coma. Use it when the record shows acute HBV plus delta-agent involvement and no hepatic coma.
Clinical signs
Clinical features vary; refer to documentation. Typical findings may include acute hepatitis symptoms such as jaundice, fatigue, abdominal discomfort, and elevated liver enzymes, with evidence of hepatitis B and delta-agent infection.
When to use this code
Use B16.1 when the provider documents acute hepatitis B with delta agent, delta superinfection, or hepatitis D coinfection in the setting of acute HBV. The diagnosis should clearly indicate that the episode is acute and that hepatic coma is absent. Check documentation if the chart only mentions hepatitis B or hepatitis D without specifying the relationship.
Do not use for
Do not use this code for chronic hepatitis B, isolated hepatitis D without acute hepatitis B, or cases with hepatic coma. If the record does not confirm acute disease or delta-agent involvement, check documentation.
Coding tip
Verify both the acute hepatitis B diagnosis and the delta-agent linkage before assigning B16.1.