ICD-10 Code E78.6 – Lipoprotein deficiency (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Lipoprotein deficiency is E78.6.
2026 ICD-10-CM Diagnosis Code E78.6 – Lipoprotein deficiency

What it is

E78.6 identifies a disorder involving abnormally low or absent lipoproteins in the blood. Use it when the record documents lipoprotein deficiency rather than a general lipid disorder.

Clinical signs

Clinical features vary; refer to documentation. Findings may include abnormal lipid testing or a stated inherited or acquired lipoprotein deficiency, but the chart should clearly name the condition.

When to use this code

Use E78.6 when the provider diagnoses lipoprotein deficiency and links it to the encounter. It may also apply when the note specifies a low-lipoprotein disorder without a more precise code. Check documentation if the record only says “abnormal lipids” or “dyslipidemia.”

Do not use for

Do not use this code for hyperlipidemia, hypercholesterolemia, or triglyceride disorders. If the diagnosis is nonspecific or another lipid abnormality is documented, code that condition instead.

Coding tip

Assign E78.6 only when the provider explicitly documents lipoprotein deficiency; otherwise, query or code the documented lipid disorder.

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