ICD-10 Code F19.988 – Other psychoactive substance use, unspecified with other psychoactive substance-induced disorder (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance use, unspecified with other psychoactive substance-induced disorder is F19.988.
2026 ICD-10-CM Diagnosis Code F19.988 – Other psychoactive substance use, unspecified with other psychoactive substance-induced disorder

What it is

This code identifies a disorder caused by an unspecified psychoactive substance, where the substance use is associated with another substance-induced mental or behavioral disorder. Use it when the record confirms a psychoactive substance but does not name a specific drug.

Clinical signs

Clinical features vary; refer to documentation. Common findings may include mood, psychotic, anxiety, or sleep-related changes linked to substance use, with the provider documenting a substance-induced condition.

When to use this code

Use this code when the clinician documents an unspecified psychoactive substance and a related induced disorder, such as intoxication-related mental changes or a substance-induced psychiatric presentation. The record should support both the substance category and the induced disorder. If the substance is named, choose the more specific code.

Do not use for

Do not use this code for a confirmed single, specific drug when a more exact ICD-10 option exists. Also avoid it when the chart does not clearly link the disorder to psychoactive substance use; check documentation.

Coding tip

Code the induced disorder only when the provider explicitly connects it to psychoactive substance use and the substance remains unspecified.

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