ICD-10 Code F19.939 – Other psychoactive substance use, unspecified with withdrawal, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance use, unspecified with withdrawal, unspecified is F19.939.
2026 ICD-10-CM Diagnosis Code F19.939 – Other psychoactive substance use, unspecified with withdrawal, unspecified

What it is

This code identifies withdrawal symptoms due to use of a psychoactive substance not otherwise specified. Use it when the substance is known to be psychoactive but the chart does not name the drug or document a more specific withdrawal code.

Clinical signs

Clinical features vary; refer to documentation. Withdrawal may include agitation, anxiety, tremor, insomnia, sweating, or other autonomic and mental status changes consistent with substance withdrawal.

When to use this code

Use this code when the provider documents withdrawal from an unspecified psychoactive substance and does not identify a more specific substance or withdrawal type. It also fits cases where the record confirms dependence or use disorder with withdrawal, but details are incomplete. Check documentation if the substance is unclear.

Do not use for

Do not use this code if the substance is identified and a more specific ICD-10-CM code is available. Do not assign it for intoxication, uncomplicated use, or nonspecific symptoms without documented withdrawal.

Coding tip

Query for the exact substance whenever possible, because unspecified withdrawal codes are less precise.

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