ICD-10 Code F19.129 – Other psychoactive substance abuse with intoxication, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance abuse with intoxication, unspecified is F19.129.
2026 ICD-10-CM Diagnosis Code F19.129 – Other psychoactive substance abuse with intoxication, unspecified

What it is

This code identifies abuse of another psychoactive substance when intoxication is present, but the specific substance is not named. Use it for documentation that confirms both abuse and intoxication, without a more precise substance detail.

Clinical signs

Clinical features vary; refer to documentation. Intoxication may be reflected by altered behavior, impaired judgment, mood changes, or reduced coordination, along with evidence of substance misuse.

When to use this code

Use this code when the record states psychoactive substance abuse with intoxication and does not identify the substance more specifically. It is appropriate when the provider documents intoxication related to misuse, but the chart lacks a named drug or agent.

If the substance is later clarified, code the more specific diagnosis instead. Check documentation for any associated complications or additional substance-related diagnoses that may need separate coding.

Do not use for

Do not use this code for dependence, uncomplicated use, or intoxication without abuse. Also avoid it when the substance is identified more specifically in the record.

Coding tip

Verify that both abuse and intoxication are documented before assigning F19.129, and query the provider if the substance type is missing but available elsewhere in the chart.

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