ICD-10 Code F19.12 – Other psychoactive substance abuse with intoxication (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Other psychoactive substance abuse with intoxication is F19.12.
2026 ICD-10-CM Diagnosis Code F19.12 – Other psychoactive substance abuse with intoxication

What it is

F19.12 identifies abuse of a psychoactive substance not classified elsewhere, with current intoxication. Use it when the record shows harmful use plus acute intoxication from that substance.

Clinical signs

Clinical features vary; refer to documentation. Intoxication may include altered behavior, impaired judgment, mood changes, or reduced coordination, along with evidence of substance abuse.

When to use this code

Use this code when the provider documents abuse of an unspecified or other psychoactive substance and states that intoxication is present. It fits encounters focused on the acute effects of use, not withdrawal or dependence alone. Check documentation for the exact substance and whether intoxication is confirmed.

Do not use for

Do not use this code for dependence, uncomplicated abuse without intoxication, or intoxication from a specifically coded substance. If the substance or clinical state is unclear, check documentation.

Coding tip

Verify both the abuse diagnosis and the intoxication component before assigning F19.12.

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