ICD-10 Code F11.28 – Opioid dependence with other opioid-induced disorder (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F11.28 – Opioid dependence with other opioid-induced disorder
What it is
F11.28 identifies opioid dependence when the patient also has another opioid-induced disorder. Use it when documentation shows both dependence and a separate opioid-related condition, but not a more specific code.
Clinical signs
Clinical features vary; refer to documentation. You may see evidence of opioid dependence plus a documented opioid-induced mental, sleep, or other disorder that is not classified elsewhere.
When to use this code
Use this code when the record clearly states opioid dependence and another opioid-induced disorder in the same encounter. It fits cases where the provider links the secondary disorder to opioid use and does not assign a more specific opioid-induced code.
Check documentation for the exact disorder name and whether it is substance-induced. If the note only says opioid use, intoxication, or withdrawal, this code is not appropriate.
Do not use for
Do not use F11.28 for uncomplicated opioid dependence alone or for opioid intoxication, withdrawal, or abuse. If the chart does not identify another opioid-induced disorder, check documentation.
Coding tip
Code the dependence and the accompanying opioid-induced disorder only when both are documented and clearly related.