ICD-10 Code E88.819 – Insulin resistance, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E88.819 – Insulin resistance, unspecified
What it is
Use this code for insulin resistance when the record does not specify a cause or associated condition. It indicates reduced tissue response to insulin, often noted as a metabolic finding rather than a standalone disease.
Clinical signs
Clinical features vary; refer to documentation. Common charted findings may include impaired glucose handling, obesity, acanthosis nigricans, or metabolic syndrome descriptors, but you should not infer these without support.
When to use this code
Assign E88.819 when the clinician documents insulin resistance without naming a more specific diagnosis. Use it for problem lists, assessment notes, or encounters focused on insulin resistance itself. If another condition explains it, code the documented condition instead.
Do not use for
Do not use this code for diabetes mellitus, prediabetes, or metabolic syndrome unless insulin resistance is separately documented. Check documentation if the record only mentions abnormal glucose or obesity.
Coding tip
Query for specificity when the note says “insulin resistance” but also suggests an underlying endocrine or metabolic disorder.