ICD-10 Code E88.818 – Other insulin resistance (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E88.818 – Other insulin resistance
What it is
E88.818 identifies insulin resistance that is documented but not better described by a more specific diagnosis. It indicates reduced response to insulin, which can affect glucose handling and metabolic risk.
Clinical signs
Clinical features vary; refer to documentation. Commonly, records may note obesity, acanthosis nigricans, impaired glucose tolerance, or a history suggesting metabolic syndrome.
When to use this code
Use this code when the provider documents insulin resistance and does not specify a more exact type or related condition. It may also apply when insulin resistance is listed as an active problem affecting evaluation or management.
Code it only when the diagnosis is clearly stated in the record. If the note describes diabetes, obesity alone, or suspected insulin resistance without confirmation, check documentation before assigning E88.818.
Do not use for
Do not use this code for diabetes mellitus, prediabetes, or obesity without documented insulin resistance. Check documentation if the record points to a different endocrine or metabolic disorder.
Coding tip
Confirm that insulin resistance is explicitly documented, and code any associated conditions separately when supported.