ICD-10 Code E88.02 – Plasminogen deficiency (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Plasminogen deficiency is E88.02.
2026 ICD-10-CM Diagnosis Code E88.02 – Plasminogen deficiency

What it is

E88.02 identifies plasminogen deficiency, a rare inherited disorder that reduces the body’s ability to break down fibrin. This can lead to abnormal fibrin-rich tissue buildup, especially on mucous membranes.

Clinical signs

Clinical features vary; refer to documentation. Commonly reported findings include ligneous lesions on the conjunctiva, gums, or other mucosal surfaces, with recurrent, thick, woody-appearing growths.

When to use this code

Use E88.02 when the clinician documents plasminogen deficiency or confirms the diagnosis in the medical record. It is appropriate for congenital or hereditary deficiency noted as the underlying condition, not merely a suspected disorder. Code it when the encounter focuses on this diagnosis or its documented manifestations.

Do not use for

Do not use this code for nonspecific bleeding problems, thrombosis, or isolated mucosal lesions without documented plasminogen deficiency. Check documentation if the record does not clearly name the disorder.

Coding tip

Verify that the provider explicitly links the diagnosis to plasminogen deficiency before assigning E88.02.

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