ICD-10 Code E80.4 – Gilbert syndrome (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E80.4 – Gilbert syndrome
What it is
E80.4 identifies Gilbert syndrome, a benign inherited disorder of bilirubin processing. It usually causes mild, intermittent unconjugated hyperbilirubinemia without evidence of liver disease.
Clinical signs
Clinical features vary; refer to documentation. Typical findings include intermittent jaundice, often triggered by fasting, illness, stress, or exertion, with otherwise normal liver function and no signs of hemolysis.
When to use this code
Use E80.4 when the provider documents Gilbert syndrome as the confirmed diagnosis. It is appropriate for encounters evaluating recurrent mild jaundice or an incidental finding of isolated unconjugated hyperbilirubinemia attributed to this condition.
Code it when the record clearly distinguishes Gilbert syndrome from other liver, biliary, or hemolytic disorders. If the diagnosis is uncertain or not documented, check documentation before assigning the code.
Do not use for
Do not use E80.4 for jaundice caused by hepatitis, biliary obstruction, hemolysis, or other confirmed liver disease. Check documentation if the chart only notes elevated bilirubin without naming Gilbert syndrome.
Coding tip
Assign E80.4 only when the clinician explicitly links the bilirubin abnormality or jaundice to Gilbert syndrome.