ICD-10 Code E80 – Disorders of porphyrin and bilirubin metabolism (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E80 – Disorders of porphyrin and bilirubin metabolism
What it is
E80 covers disorders that affect how the body makes, breaks down, or handles porphyrins and bilirubin. These conditions can lead to abnormal pigment buildup or jaundice-related findings.
Clinical signs
Clinical features vary; refer to documentation. Commonly documented findings include jaundice, dark urine, anemia-related features, or photosensitivity, depending on the specific disorder.
When to use this code
Use E80 when the provider documents a porphyrin or bilirubin metabolism disorder without assigning a more specific subtype. It may also apply when the record describes a hereditary or acquired pigment metabolism problem under this category. Check documentation for the exact diagnosis.
Do not use for
Do not use this code for nonspecific jaundice or liver disease unless the provider identifies a porphyrin or bilirubin metabolism disorder. Avoid it when a more specific ICD-10 code is documented.
Coding tip
Always code to the most specific E80 subcategory supported by the documentation.