ICD-10 Code E78.5 – Hyperlipidemia, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Hyperlipidemia, unspecified is E78.5.
2026 ICD-10-CM Diagnosis Code E78.5 – Hyperlipidemia, unspecified

What it is

E78.5 identifies hyperlipidemia when the record does not specify the lipid abnormality. Use it for elevated blood lipids documented without a more specific type.

Clinical signs

Clinical features vary; refer to documentation. The diagnosis is usually based on abnormal lipid testing or a provider statement of hyperlipidemia, without further detail.

When to use this code

Use E78.5 when the provider documents hyperlipidemia, mixed hyperlipidemia, or dyslipidemia without naming a more specific codeable condition. It also fits when the chart confirms a lipid disorder but the exact type is not stated. If the record specifies a different lipid disorder, code that instead.

Do not use for

Do not use E78.5 for isolated cholesterol screening results or for a more specific lipid disorder already documented. Check documentation if the diagnosis is secondary to another condition.

Coding tip

Query for specificity when the note says “high cholesterol” or “dyslipidemia” but does not clearly state the diagnosis.

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