ICD-10 Code E74.10 – Disorder of fructose metabolism, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Disorder of fructose metabolism, unspecified is E74.10.
2026 ICD-10-CM Diagnosis Code E74.10 – Disorder of fructose metabolism, unspecified

What it is

E74.10 identifies an unspecified disorder of fructose metabolism. Use it when the record confirms a fructose metabolism problem but does not name a specific inherited or acquired subtype.

Clinical signs

Clinical features vary; refer to documentation. Fructose-related metabolic disorders may present with feeding intolerance, vomiting, abdominal pain, hypoglycemia, or abnormal liver findings, but the specific pattern should be documented.

When to use this code

Use this code when the provider documents a disorder of fructose metabolism and does not specify the exact condition. It may also fit when the chart notes fructose intolerance or related metabolic dysfunction without further detail. Check documentation for the most specific diagnosis available.

Do not use for

Do not use this code when a more specific fructose metabolism disorder is documented. Do not confuse it with general dietary intolerance, food allergy, or nonspecific gastrointestinal symptoms without a confirmed metabolic disorder.

Coding tip

If the diagnosis is vague, query for the exact metabolic disorder before assigning E74.10.

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