ICD-10 Code E72.59 – Other disorders of glycine metabolism (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E72.59 – Other disorders of glycine metabolism
What it is
E72.59 identifies inherited or acquired disorders affecting glycine metabolism that do not fit a more specific ICD-10 diagnosis. Use it when documentation states a glycine metabolic disorder, but the exact subtype is not named.
Clinical signs
Clinical features vary; refer to documentation. Reported findings may include developmental delay, neurologic abnormalities, or recurrent metabolic symptoms, depending on the specific disorder.
When to use this code
Use this code when the provider documents an unspecified or other glycine metabolism disorder and no more specific code is supported. It is appropriate when the record confirms a glycine pathway abnormality but does not identify a named condition.
Code from the most specific diagnosis available in the chart. If the note only says “glycine disorder” or “other glycine metabolism defect,” E72.59 may be the correct choice.
Do not use for
Do not use this code for clearly identified glycine-related conditions that have their own ICD-10 code. Check documentation if the record actually describes a different amino acid or metabolic disorder.
Coding tip
Confirm the exact metabolic diagnosis in the assessment, not just in lab history or problem lists, before assigning E72.59.