ICD-10 Code E72.539 – Primary hyperoxaluria, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E72.539 – Primary hyperoxaluria, unspecified
What it is
Primary hyperoxaluria, unspecified is a hereditary disorder in which the body produces too much oxalate. The excess oxalate can build up in the kidneys and urinary tract.
Clinical signs
Clinical features vary; refer to documentation. Common findings include recurrent kidney stones, hematuria, nephrocalcinosis, or progressive kidney dysfunction in a patient with a suspected inherited oxalate disorder.
When to use this code
Use this code when the provider documents primary hyperoxaluria but does not specify the subtype. It also fits cases described as hereditary oxalate overproduction with no further detail in the record. Check documentation if the note distinguishes a specific genetic type.
Do not use for
Do not use it for secondary hyperoxaluria from diet, bowel disease, or malabsorption. Avoid this code when the record identifies a specific primary hyperoxaluria type.
Coding tip
Code the unspecified option only when the chart supports primary hyperoxaluria and the subtype is not stated.