ICD-10 Code A52.3 – Neurosyphilis, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Neurosyphilis, unspecified is A52.3.
2026 ICD-10-CM Diagnosis Code A52.3 – Neurosyphilis, unspecified

What it is

A52.3 identifies neurosyphilis when the infection involves the central nervous system but the specific neurologic form is not documented. Use it for confirmed neurosyphilis without further subtype detail.

Clinical signs

Clinical features vary; refer to documentation. Findings may include neurologic, psychiatric, ocular, or auditory involvement consistent with syphilitic infection of the nervous system.

When to use this code

Use this code when the provider documents neurosyphilis but does not specify asymptomatic, meningovascular, tabes dorsalis, or general paresis. It also fits cases where the record confirms CNS involvement from syphilis, but the subtype remains unclear.

Do not use for

Do not use A52.3 for syphilis without nervous system involvement. If the chart names a more specific neurosyphilis form, code that diagnosis instead.

Coding tip

Check the note for the exact neurosyphilis subtype before assigning A52.3.

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