ICD-10 Code E22.9 – Hyperfunction of pituitary gland, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E22.9 – Hyperfunction of pituitary gland, unspecified
What it is
E22.9 identifies pituitary gland overactivity when the specific hormone excess or pituitary disorder is not documented. Use it for an unspecified hyperfunction of the pituitary gland.
Clinical signs
Clinical features vary; refer to documentation. Findings may reflect excess pituitary hormone production, but the record must support pituitary hyperfunction rather than another endocrine disorder.
When to use this code
Use E22.9 when the provider documents pituitary hyperfunction but does not name the exact condition, such as a specific adenoma-related hormone excess. It also fits cases where the chart confirms pituitary overactivity and the detail needed for a more specific code is missing. Check documentation before assigning it.
Do not use for
Do not use this code for clearly identified pituitary disorders with a more specific ICD-10-CM diagnosis. If the record supports another endocrine cause or a named pituitary syndrome, code that condition instead.
Coding tip
Query for the exact pituitary disorder or hormone excess whenever possible, because E22.9 is an unspecified code.