ICD-10 Code E23 – Hypofunction and other disorders of the pituitary gland (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Hypofunction and other disorders of the pituitary gland is E23.
2026 ICD-10-CM Diagnosis Code E23 – Hypofunction and other disorders of the pituitary gland

What it is

E23 covers reduced pituitary function and other non-neoplastic pituitary disorders. Use it when the record identifies pituitary hypofunction, but does not specify a more detailed diagnosis.

Clinical signs

Clinical features vary; refer to documentation. Commonly, records describe hormone deficiency patterns, growth or pubertal delay, menstrual changes, fatigue, or symptoms related to pituitary hormone loss.

When to use this code

Use E23 when the clinician documents hypopituitarism, pituitary insufficiency, or another pituitary disorder that is not a tumor and is not coded more specifically. It also fits cases where the pituitary problem is confirmed, but the exact subtype is not stated. Check documentation for the underlying cause and any associated endocrine deficits.

Do not use for

Do not use E23 for pituitary neoplasms, which are coded elsewhere. If the chart names a more specific pituitary disorder or a different endocrine condition, code that diagnosis instead.

Coding tip

Confirm whether the provider documented hypofunction, another pituitary disorder, or a more specific endocrine deficiency before assigning E23.

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