ICD-10 Code D68.5 – Primary thrombophilia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D68.5 – Primary thrombophilia
What it is
Primary thrombophilia is an inherited tendency to form abnormal blood clots. Use this code for a documented clotting disorder that is not caused by another medical condition.
Clinical signs
Clinical features vary; refer to documentation. Common clues include recurrent venous thromboembolism, clotting at a young age, or a family history of thrombosis.
When to use this code
Use D68.5 when the record states primary, hereditary, or inherited thrombophilia. It may support encounters for evaluation after an unexplained clot or for a known clotting disorder without an acquired cause.
Code it only when the provider documents the condition clearly. If the chart instead identifies an acquired hypercoagulable state or another specific disorder, use the documented diagnosis.
Do not use for
Do not use this code for thrombosis alone, a personal history of clotting, or an acquired coagulation disorder. Check documentation if the cause of hypercoagulability is not specified.
Coding tip
Look for terms like “inherited thrombophilia” or a named genetic clotting disorder before assigning D68.5.