ICD-10 Code D61.82 – Myelophthisis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D61.82 – Myelophthisis
What it is
Myelophthisis is bone marrow failure caused by marrow infiltration or replacement. It leads to reduced production of blood cells because normal marrow tissue is crowded out.
Clinical signs
Clinical features vary; refer to documentation. Common findings include anemia, fatigue, and signs of pancytopenia, with evidence of an underlying infiltrative process affecting the marrow.
When to use this code
Use this code when the provider documents myelophthisis or myelophthisic anemia due to marrow replacement. It may apply when marrow involvement is linked to malignancy, fibrosis, or other infiltrative disease. Check documentation for the stated cause and whether the diagnosis is confirmed.
Do not use for
Do not use this code for simple anemia without marrow infiltration or for unspecified bone marrow disorders. If the record does not clearly support myelophthisis, check documentation.
Coding tip
Code the documented underlying condition separately when it is reported and supported.