ICD-10 Code D61.1 – Drug-induced aplastic anemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D61.1 – Drug-induced aplastic anemia
What it is
Drug-induced aplastic anemia is a bone marrow failure condition caused by a medication or other drug exposure. It leads to reduced production of blood cells, so the marrow cannot make enough red cells, white cells, and platelets.
Clinical signs
Clinical features vary; refer to documentation. Common findings include fatigue, pallor, infections, easy bruising, bleeding, and pancytopenia with a hypocellular marrow when confirmed.
When to use this code
Use D61.1 when the record links aplastic anemia directly to a drug or medication exposure. The provider should document the causal relationship, such as a suspected adverse drug effect or confirmed drug-induced marrow suppression. If the cause is not stated, check documentation before assigning this code.
Do not use for
Do not use this code for aplastic anemia with no documented drug cause, or for other cytopenias without marrow failure. Check documentation if the anemia is due to chemotherapy, radiation, or another specified cause.
Coding tip
Verify that the drug cause is explicitly documented before coding D61.1.