ICD-10 Code D55.2 – Anemia due to disorders of glycolytic enzymes (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D55.2 – Anemia due to disorders of glycolytic enzymes
What it is
This code identifies anemia caused by inherited or acquired defects in glycolytic enzymes, which reduce red blood cell energy production. Use it when documentation specifically links the anemia to a glycolytic enzyme disorder.
Clinical signs
Clinical features vary; refer to documentation. Patients may show signs of anemia such as fatigue, pallor, weakness, or shortness of breath, along with evidence of an underlying enzyme defect.
When to use this code
Use D55.2 when the record states anemia due to a disorder of glycolytic enzymes, or names a specific glycolytic enzyme defect as the cause. You should code it only when the provider clearly documents the causal relationship. If the chart mentions anemia without that link, check documentation.
Do not use for
Do not use this code for anemia from blood loss, iron deficiency, hemolysis without enzyme involvement, or unspecified hereditary anemia. If the cause is unclear, check documentation.
Coding tip
Look for explicit provider wording connecting the anemia to the enzyme disorder before assigning D55.2.