ICD-10 Code C92.2 – Atypical chronic myeloid leukemia, BCR/ABL-negative (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C92.2 – Atypical chronic myeloid leukemia, BCR/ABL-negative
What it is
C92.2 identifies atypical chronic myeloid leukemia that is negative for the BCR/ABL fusion. Use it for this uncommon myeloid neoplasm when the diagnosis is documented as BCR/ABL-negative and not another leukemia subtype.
Clinical signs
Clinical features vary; refer to documentation. Typical findings may include leukocytosis, splenomegaly, and evidence of a chronic myeloproliferative or myelodysplastic process, but you should code only when the diagnosis is clearly stated.
When to use this code
Use C92.2 when the provider documents atypical chronic myeloid leukemia, BCR/ABL-negative, or an equivalent term such as atypical CML. Confirm that the record distinguishes it from classic chronic myeloid leukemia and other BCR/ABL-positive myeloproliferative disorders. If the documentation is unclear, check documentation before assigning the code.
Do not use for
Do not use this code for chronic myeloid leukemia with BCR/ABL positivity, chronic myelomonocytic leukemia, or other specified leukemias. If the chart names a different myeloid neoplasm, select the documented diagnosis instead.
Coding tip
Look for the exact phrase “BCR/ABL-negative” in the diagnosis, pathology, or hematology note before coding C92.2.