ICD-10 Code C92.10 – Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission is C92.10.
2026 ICD-10-CM Diagnosis Code C92.10 – Chronic myeloid leukemia, BCR/ABL-positive, not having achieved remission

What it is

C92.10 identifies chronic myeloid leukemia, BCR/ABL-positive, when the disease has not achieved remission. Use it for documented active CML in the chronic phase or persistent disease, not for remission status.

Clinical signs

Clinical features vary; refer to documentation. Common findings in CML may include fatigue, splenomegaly, leukocytosis, and abnormal peripheral blood or bone marrow results confirming BCR/ABL-positive disease.

When to use this code

Use this code when the provider documents BCR/ABL-positive chronic myeloid leukemia and states it has not achieved remission. It fits ongoing active disease, initial diagnosis before remission is documented, or persistent disease after prior therapy. If remission status is unclear, check documentation.

Do not use for

Do not use this code for CML in remission or for leukemia type not specified as BCR/ABL-positive. Do not assign it if the record only says “history of leukemia” without active disease.

Coding tip

Verify both the BCR/ABL-positive designation and the “not having achieved remission” status before assigning C92.10.

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