ICD-10 Code C81.34 – Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C81.34 – Lymphocyte depleted Hodgkin lymphoma, lymph nodes of axilla and upper limb
What it is
C81.34 identifies lymphocyte-depleted Hodgkin lymphoma involving lymph nodes in the axilla or upper limb. Use it when documentation specifies this Hodgkin lymphoma subtype and nodal site.
Clinical signs
Clinical features vary; refer to documentation. Hodgkin lymphoma commonly presents with enlarged lymph nodes, sometimes with constitutional symptoms such as fever, night sweats, or weight loss.
When to use this code
Use this code when the provider documents lymphocyte-depleted Hodgkin lymphoma affecting axillary or upper-limb lymph nodes. It is appropriate for confirmed diagnoses, pathology reports, or oncology assessments that identify both the subtype and site.
Choose the documented site-specific code rather than an unspecified Hodgkin lymphoma code when the record supports it. Check documentation if laterality, nodal region, or histology is unclear.
Do not use for
Do not use it for other Hodgkin lymphoma subtypes, unspecified Hodgkin lymphoma, or non-Hodgkin lymphomas. Do not assign it if the affected nodal site is not documented.
Coding tip
Match both the histology and the anatomic site in the record before coding.