ICD-10 Code C49.2 – Malignant neoplasm of connective and soft tissue of lower limb, including hip (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C49.2 – Malignant neoplasm of connective and soft tissue of lower limb, including hip
What it is
C49.2 identifies a malignant tumor arising from connective or soft tissue in the lower limb, including the hip. Use it when the record documents a primary soft tissue cancer in that anatomic site.
Clinical signs
Clinical features vary; refer to documentation. Soft tissue sarcomas may present as a growing mass, pain, swelling, or limited limb function, but diagnosis should be based on documented malignant neoplasm.
When to use this code
Use C49.2 when the provider specifies malignant connective or soft tissue neoplasm of the leg, thigh, knee region, or hip. It also fits when pathology or imaging supports a malignant soft tissue tumor in that location and no more specific site code is documented.
Do not use for
Do not use this code for benign soft tissue tumors, metastatic disease to the lower limb, or bone malignancies. Check documentation if the lesion is described only as uncertain, benign, or secondary.
Coding tip
If the note gives a more exact site within the lower limb, code to the most specific documented location.